![]() ![]() Fox Foundation for Parkinson’s Research (MJFF) and The Silverstein Foundation for Parkinson’s with GBA, the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and Innosuisse, and through a Swiss Accelerator Innovation Project supported by Innosuisse. Gain’s lead program in Parkinson’s disease has been awarded funding support from The Michael J. ![]() Gain’s pipeline spans neurodegenerative diseases, lysosomal storage disorders (LSDs), metabolic disorders, as well as other diseases that can be targeted through protein degradation, such as oncology. By binding to allosteric binding sites, the small molecules discovered with SEE-Tx provide opportunities for a range of drug-protein interactions, including protein stabilization, protein destabilization, targeted protein degradation, allosteric inhibition, and allosteric activation. With its proprietary computational discovery platform SEE-Tx®, Gain Therapeutics is transforming drug discovery by identifying novel allosteric targets on proteins involved in diseases across the full spectrum of therapeutic areas. is a biotechnology company leading the discovery and development of allosteric small molecule therapies. To listen to the webcast or schedule meetings with management, please contact your BTIG representative. (Nasdaq: GANX) (“Gain”, or the “Company”), a biotechnology company leading the discovery and development of allosteric small molecule therapies, today announced that members of management will participate in a fireside chat at the 2023 BTIG Virtual Biotechnology Conference on Tuesday, August 8 at 9:30 a.m. I can only dream.BETHESDA, Md., J(GLOBE NEWSWIRE) - Gain Therapeutics, Inc. The most amazing thing would be hardware like this coupled with a custom 240x160 OLED display. Nobody makes LCD screens at GBA res anymore and if you want to go high res enough to overcome upscaling issues the cost goes up. I assume that issue stems from the difficulty in sourcing a new screen. It just seems like they crammed the GBA clone hardware into a piece of hardware not designed for it. But combined with emulation it can also play GB, GBC, Sega Master System, Game Gear, NES and PC Engine. If you want a larger image you wind up with upscaling artefacts. The Revo K101 Plus is primarily built for playing your best Gameboy Advance games, period. If you want 1:1 pixels you have to run it in a tiny window which I don't feel is acceptable for a device designed to play GBA games exclusively. My issue is that they clearly selected the wrong screen for the job. Saturn doesn't support the resolution used by the original game so they had to upscale leading to ugly artifacts. This is actually the same issue that ruined SotN on Sega Saturn. Like, you'll have one drawn pixel line up with one pixel on the screen while the drawn pixel next to it will occupy two physical pixels creating an ugly scaled effect. What you end up with is variable pixel width. The screen is higher res than a GBA but not high res enough to support scaling. I'd suggest skipping this if you are planning on using the system as a multiple system emulator.Ĭlick to expand.It's not the aspect ratio that's the issue - it's the misalignment of the pixels. A lot of the GBC games also suffered from slowdown issues when attempting to play the games and there is no way to disable the Super Game Boy borders to make the games full screen. NES and some GBC games suffer from some horrible audio issues when using the system emulator.Other GBA games worked great, and this only happened with the NES series of GBA releases. For the most part, they run slowly and have issues detecting button presses. GBA NES Classics run poorly on the console. ![]() Being able to remap controls to button combinations would have been awesome considering that the Street Fighter games allow you to map controls to simultaneous button presses, but unfortunately you can not remap controls to the spare buttons on the controller. You may be able to wear them down and make them softer to the press in the future, but it makes for doing some inputs for fighting games difficult to pull off.
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